The X meeting of the Spanish Drug Discovery Network took place in Bilbao on November 22nd and 23rd, 2018. This international conference is focused on early drug discovery from Academia and Industry and this year, the main scientific topics treated were related to Computational Predictive Methods and New Models for Biologically Relevant Assays. Dr. Bastien Cautain and Thomas Mackenzie both scientists of the Screening and Target validation department at MEDINA presented the work “Natural Products as new sources of nuclear translocation inhibitors using High Content Bio-Imaging”.