Fundación MEDINA attended SLAS Europe 2018 and presented its integrated HTS platform for Natural Products Discovery. Examples were given of different drug discovery programs developed at MEDINA from its microbial Natural products libraries: discovery of a novel family of antibiotic natural products with Gram-negative broad spectrum, search for antitumor compounds in the nuclear translocation-based assay, Identification of a novel Inhibitor of VHL/HIF Pathway and detection of a novel molecule with protective effects on neurodegenerative in vitro models. These primary screens are part of the MEDINA Screening Platform where HTS and HCS are integrated to develop new projects using the know-how acquired from many years of research.
